Genetic regulatory signatures underlying islet gene expression and type 2 diabetes, Varshney et al.

The full paper is available here: doi:10.1073/pnas.1621192114

You can follow this link to our dynamic islet eQTL explorer.

The data available here includes chromatin state predictions in various tissues; peak calls made on islet, adipose, and lymphoblastoid tissue data referenced in the paper; and transcription factor footprinting for islet data (ABCU196 and ABE1388).

ABCU196 is Islet 1 from the paper; ABE1388 is Islet 2.

Each subset of the data is available in its own subdirectory, and also in a single file. For example, the ABCU196 footprints are available in individual files by transcription factor in the footprints.abcu196 directory, or all together in footprints.abcu196.tar.gz.

The full cis-eQTL scan results are available in the cis-eQTL-scan directory. Allele 1 is the effect allele.

All of the data available here, except the cis-eQTL scan results, are included in everything.tar.gz.

All coordinates are based on hg19.

Icon  Name                                   Last modified      Size  Description
[PARENTDIR] Parent Directory                                            -   
[DIR] footprints.abcu196/                    2017-03-13 13:03    -   
[DIR] footprints.abe1388/                    2017-03-22 09:53    -   
[DIR] cis-eQTL-scan/                         2017-04-21 08:34    -   
[DIR] atacseq_IsletMuscleAdiposeGM/          2017-09-14 16:49    -   
[DIR] peaks.broad/                           2017-09-14 17:51    -   
[DIR] atacseq_fastqc/                        2018-03-12 23:05    -   
[DIR] chromatin_states/                      2018-09-10 13:09    -   
[   ] footprints.abe1388.tar.gz              2017-03-13 12:49  1.2G  
[   ] footprints.abcu196.tar.gz              2017-03-13 12:50  2.3G  
[   ] chromatin_states.tar.gz                2017-03-13 12:51   65M  
[   ] peaks.broad.tar.gz                     2017-03-13 13:46   16M  
[   ] everything.tar.gz                      2017-03-13 18:47  3.6G  
[   ] footprints.abcu196.updated_2018.tar.gz 2018-05-16 14:12  2.3G  
[   ] footprints.abe1388.updated_2018.tar.gz 2018-05-16 14:13  1.2G